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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKZ
All Species:
11.21
Human Site:
S595
Identified Species:
18.97
UniProt:
Q13574
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13574
NP_001099010.1
1117
124128
S595
E
P
V
S
K
I
L
S
H
V
E
E
G
N
V
Chimpanzee
Pan troglodytes
XP_508395
1117
124129
S595
E
P
V
S
K
I
L
S
H
V
E
E
G
N
V
Rhesus Macaque
Macaca mulatta
XP_001102461
1084
120447
S562
E
P
V
S
K
I
L
S
H
V
E
E
G
N
V
Dog
Lupus familis
XP_540755
766
85714
A316
K
S
G
G
N
Q
G
A
K
I
I
Q
S
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
F479
P
E
K
F
N
S
R
F
R
N
K
M
F
Y
A
Rat
Rattus norvegicus
O08560
929
103991
F479
P
E
K
F
N
S
R
F
R
N
K
M
F
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
D505
G
N
P
G
E
H
R
D
F
E
P
Q
R
H
D
Chicken
Gallus gallus
NP_001026363
953
106222
G503
A
F
S
D
F
L
T
G
S
S
K
D
L
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
V574
D
L
A
K
H
I
K
V
V
C
D
G
T
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
R925
E
P
I
G
K
I
L
R
E
I
G
M
S
Q
C
Honey Bee
Apis mellifera
XP_396522
837
92900
D387
L
V
R
R
K
W
K
D
L
S
E
F
V
M
L
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
S487
G
T
V
G
W
V
L
S
T
L
D
N
L
N
W
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
R365
F
K
K
V
P
N
L
R
I
L
A
C
G
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
G278
S
A
D
T
G
N
S
G
S
N
C
D
E
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.3
65.1
N.A.
78.2
79.3
N.A.
54.7
67.8
N.A.
60.4
N.A.
31.9
31.2
31.6
43.1
Protein Similarity:
100
99.8
91.2
66.6
N.A.
80.5
80.5
N.A.
65.8
74.8
N.A.
70.6
N.A.
46.1
46.2
46.3
55
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
0
0
N.A.
6.6
N.A.
33.3
13.3
26.6
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
6.6
6.6
N.A.
20
20
N.A.
33.3
N.A.
46.6
20
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
8
0
0
8
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
8
% C
% Asp:
8
0
8
8
0
0
0
15
0
0
15
15
0
8
15
% D
% Glu:
29
15
0
0
8
0
0
0
8
8
29
22
8
0
0
% E
% Phe:
8
8
0
15
8
0
0
15
8
0
0
8
15
8
0
% F
% Gly:
15
0
8
29
8
0
8
15
0
0
8
8
29
8
0
% G
% His:
0
0
0
0
8
8
0
0
22
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
36
0
0
8
15
8
0
0
0
0
% I
% Lys:
8
8
22
8
36
0
15
0
8
0
22
0
0
0
8
% K
% Leu:
8
8
0
0
0
8
43
0
8
15
0
0
15
0
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
22
0
8
0
% M
% Asn:
0
8
0
0
22
15
0
0
0
22
0
8
0
29
0
% N
% Pro:
15
29
8
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
15
0
8
0
% Q
% Arg:
0
0
8
8
0
0
22
15
15
0
0
0
8
0
0
% R
% Ser:
8
8
8
22
0
15
8
29
15
15
0
0
15
8
0
% S
% Thr:
0
8
0
8
0
0
8
0
8
0
0
0
8
0
8
% T
% Val:
0
8
29
8
0
8
0
8
8
22
0
0
8
0
22
% V
% Trp:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _